OPSYNVI® Is a Once-Daily Pill With a Dual-Pathway Approach
Discover a combination therapy that targets two foundational PAH pathways.
Starting OPSYNVI®
If you are not currently on any PAH therapy or are transitioning
from an ERA alone:
One OPSYNVI® pill (macitentan 10mg/tadalafil 20mg), once daily for 1 week.
If tolerated, the doctor will increase your dose to one OPSYNVI® pill (macitentan 10mg/tadalafil 40mg), once daily.
ERA = endothelin receptor antagonist
If you are transitioning from a PDE5i alone or taking the combination of an ERA and a PDE5i as individual pills:
Start with one OPSYNVI® pill (macitentan 10mg/tadalafil 40mg), once daily.
PDE5i = phosphodiesterase type 5 inhibitor
The pills illustrated above are not actual size.
How to Take OPSYNVI®
Once you and your healthcare provider decide that OPSYNVI® is right for you, OPSYNVI® will be mailed to you by a specialty pharmacy.
- Take OPSYNVI® exactly as instructed by your healthcare provider. Do not stop taking OPSYNVI® unless your healthcare provider tells you to do so.
- OPSYNVI® is an oral pill of macitentan
10-mg/tadalfil 40-mg taken once daily by mouth. - OPSYNVI® can be taken with or without food.
- Take the pill whole and do not cut, crush, or chew OPSYNVI® pills.
- If you accidentally take too much OPSYNVI®, contact your healthcare provider or go to the nearest hospital emergency room right away.
- If you miss a dose of OPSYNVI®, take it as soon as you remember that day. Take the next dose at your regular time. Do not take 2 doses at the same time to make up for a missed dose.
Learn How OPSYNVI® Can Help You Manage Your PAH
Download the OPSYNVI® brochure for quick access to the benefits and patient support options available to you.
Download Brochure
